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L–Citrulline is an amino acid that has been found to play an important role in nitric oxide (NO) metabolism and regulation. L-Citrulline is converted to L-Arginine in the body, leading to increases in both L-Arginine and nitric oxide. Increased production of nitric oxide promotes vascular dilation, which helps support normal oxygen and blood circulation throughout the body.
The pharmacokinetic advantage of L-Citrulline is that it is not subject to any elimination by the liver prior to entering the bloodstream. Conversely, L-Arginine is subject to extensive elimination by the gut wall and liver. (26)
The majority of L-Citrulline is converted to L-Arginine in the kidney. (3)
Once in circulation, L-Arginine is readily converted into L-Citrulline and nitric oxide, which in turn serves as an L-Arginine precursor.
|Directions of Use||
As a dietary supplement, mix 1 scoop in your favorite beverage or protein shake twice daily.
Warnings: Consult your physician prior to using this product if you are pregnant, nursing, under 18 years of age, taking medication or have a medical condition. Immediately discontinue use and contact your physician if any adverse reactions occur. Keep out of reach of children. Store in a cool dry place away from excessive heat. Serving scoop included (may settle to the bottom during shipping.)
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.